What is the difference between fantasy and science fiction? At first glance, it can seem like a simple question. Science fiction often takes place in a dystopian society sometime in the future and contains elements of advanced technology. A fantasy story, on the other hand, is usually set in the fantasy realm and includes mythical creatures and supernatural powers. Though the similarities between these two genres are readily apparent, there are more similarities and crossovers between the two genres than first meets the eye.